Quitting Smoking and Products to Help

  Contributed by: Lauren Mareschal, Pharm.D.  Candidate

                        UMKC School of Pharmacy

Text Box: Congratulations!  You have finally made the decision to quit smoking.  After setting your official quit date, you will have to decide what product, if any, you will use for assistance.  The following is a brief description of your options with some advantages and disadvantages.

Cold Turkey:
This method of quitting requires true self-control and determination.  However, nicotine withdrawal will happen whether you use the cold turkey method or a nicotine containing product, so why not just get the withdrawal over with right away?  Besides, with no product to buy, it is by far the cheapest.  When combined with a smoking cessation program, this method works especially great for some people!

Tapering:
You can taper off your cigarettes, which again requires self-control since you will still have cigarettes around the house.  However, this is another cheap option.  QuitKey® and SmokeSignals® are two handheld computerized machines that assist with tapering based on your current smoking level.  Obviously, this is not as cheap as tapering on your own but might help you stick to your taper.

Gum (Nicorette® or generic product):
The gum is sugar-free and available in tobacco-like, mint, and orange flavors.  However, it is not as tasty as normal gum.  It must be alternated between slow chewing and “parking” between the gum and cheek at the first sign of mint or citrus flavor or tingle.  If the gum is accidentally ingested, it can nausea, vomiting, hiccups, or heartburn.  So, this is not a good option if you have peptic ulcer disease.  It is also not good for people with dentures or for people who have a work environment that does not allow gum chewing.  It is a great option if you have an oral fixation.  You cannot eat or drink 15 minutes before or while using the gum.  If you smoke >25 cigarettes a Text Box: day, start on 4 mg.  If you smoke <25 cigarettes a day, start on 2 mg.  You will use the gum for 12 weeks.  Many patients under treat themselves, so it is important to closely follow the dosing on the box.

Lozenge (Commit® or generic product):
This is another great product if you have an oral fixation, and it tastes better than the gum.  It cannot be chewed or swallowed whole, because it will cause nausea, vomiting, hiccups, and heartburn.  Avoid if you have peptic ulcer disease.  Start with 2 mg if you smoke >30 minutes after waking.  Start with 4 mg if you smoke <30 minutes after waking.  Follow the directions on the box closely to assure that you don’t under treat.  Like the gum, you cannot eat or drink 15 minutes before or while using the lozenge (lasts about 20-30 minutes).  You will use the product for 12 weeks.

Patch (Nicoderm®, Nicotrol®, or generic product): 
Nicotrol® lasts 16 hours and is great if you do not have morning cravings.  Nicoderm CQ® lasts 24 hours and is great if you have morning cravings, but wearing it overnight can cause nightmares.  The step that you start on is based on the brand and whether you smoke more or less than 10 cigarettes a day.  You will be on the product for 8-10 weeks.  The patch must be placed on clean, dry, hairless skin of the upper body.  A new patch is applied daily and should be rotated to different sites.  Do not use this product if your skin is easily irritated, because it can cause itching and burning.  You must watch for an allergic reaction.  The patch can get wet but cannot be cut.  Be sure to fold the sticky sides together when disposing.  A benefit to the patch is that it can easily be concealed.

Nasal spray (Nicotrol NS®):
This product can cause a lot of nasal/Text Box: throat irritation and may result in dependence.  It requires a prescription.

Inhaler (Nicotrol®):
The inhaler mimics the hand-to-mouth ritual of smoking but can cause throat or mouth irritation and is not good for patients with bronchospasms.  It requires a prescription.

Oral medications:
Buproprion SR (Wellbutrin SR®):  This medication is also used as an antidepressant but cannot be used in patients who have seizures or anorexia or in patients who are abruptly discontinuing alcohol or sedatives.  It is often taken for 12 weeks with side effects such as insomnia and dry mouth.  It can be used in combination with any of the nicotine replacements, such as lozenges, gum or the patch.
Varenicline tartrate (Chantrix®):  This medication was recently approved by the FDA.  It is taken once or twice daily for 12-24 weeks.  It has shown more success in trials compared to bupropion but may not be available until summer 2006.  Also, bupropion has more safety evidence.  The most common side effects are nausea, constipation, gas, vomiting, and changes in dreaming.

Good luck with quitting!  You are taking steps to improve your health and the health of those around you!  For additional information, talk to your pharmacist or physician or visit www.smokefree.gov.  
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