Know Your Over-the-Counter (OTC) Pain and Fever
Medications
Contributed by: Grace Kuweruza, Pharm.D. Candidate UMKC School of
Pharmacy |




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Here is a guide to help you choose the best medications for your condition: |
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Acetaminophen |
Aspirin |
Ibuprofen |
Naproxen |
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Brand-name examples |
Tylenol® |
Bayer® Aspirin, St. Joseph® |
Advil®, Motrin® |
Aleve ® |
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Uses |
Very effective pain and fever reducer. Does not contain anti-inflammatory activities.
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Great choice for arthritis pain and migraine. Effective fever reducer and anti-inflammatory. Low dose aspirin (Baby aspirin = 81 mg) if taken daily may reduce the risk of heart attacks or angina. |
Great pain reliever, fever reducer and anti- inflammatory. Very helpful for arthritis and musculoskeletal pain, menstrual cramps, and headache.
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Like Ibuprofen, great pain reliever, fever reducer, and anti inflammatory. Very effective for arthritis and musculoskeletal pain, menstrual cramps, and headache. |
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Length of pain relieve |
4-6 hours |
4-6 hours |
6-8 hours |
12 hours |
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Side effects |
Not hard on digestive system. Can cause liver damage when used long term at high dose. |
Difficult on stomach lining and digestive system. |
Can be difficult on your stomach. Should be taken with food. |
Like Ibuprofen and Aspirin, can be hard on stomach. |
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Safe for children |
Excellent for children |
Should not be taken by children and teenagers |
Safe for children |
Very strong and too long lasting for children |