Celiac Sprue Disease
  Contributed by: Elizabeth A. Minich, Pharm.D. Candidate
                        UMKC School of Pharmacy

What is Celiac Sprue disease?
Celiac sprue disease is a genetic disease that causes a persons small intestine to be damaged by a protein called gluten. A genetic disease means that it is passed down to family members from generation to generation.  Celiac sprue is an autoimmune disease, which means that the person's body produces substances to attack gluten called antibodies, which in turn causes damage to the person's small intestine.  Celiac Sprue damages the villi in our small intestine.  The villi in our small intestine are responsible for absorbing the nutrients in food.  They are primarily involved in nourishing our body. 

You may be wondering how you know if you might have this disease.  Some typical symptoms include abdominal pain, swelling, stomach upset, and weight loss.  Some individuals may not have any symptoms.  Celiac sprue is a disease that is much under diagnosed. 

If you have been diagnosed with celiac sprue it is very important to avoid anything that contains gluten. Some common gluten containing items include: 

breads, cookies, pastas, frozen french fries, soy sauce, and rice cereals.  Some uncommon items that contain gluten include common household cleaners and cosmetics.  The most important thing to know is that celiac sprue is a lifelong disease and gluten will need to be avoided lifelong.  This will in turn require careful label reading on anything from food to anything that you purchase at the store.

Celiac sprue can be a huge change in a person's life.  This requires that the individual have a strong support network.  The individual will have to avoid gluten lifelong.  All of the family members and friends must be educated to adequately improve the quality of life of the individual.  Anytime the individual goes out to eat or goes to another persons home to eat requires them to be extremely careful.  Gluten can set off this terrible response to his/her body rather easily.

The good news about celiac sprue is that no surgery or any long term medications are required to treat this disease.  The only treatment is a gluten-

free diet.  Maintaining a gluten-free diet will improve the intestinal lining in as little as three to six days.  The lining of the intestine will go back to normal in three to six months.  In other words, the disease is very curable by just avoiding the culprit.  The diet is really a great intervention because gluten is not needed by our body for any nutritional value.  Providing the individual's body with a gluten-free diet will do nothing but have a great impact on his/her body.  This will allow the person to have a longer and healthier life. 

For more information on celiac sprue, consult your pharmacist or physician, and/or go to www.csaceliacs.org

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