The Truth about Botox
Contributed by: Mark Ravis, Pharm.D. Candidate
                      KU School of Pharmacy

Botox injections are the fastest-growing cosmetic procedure in the industry, according to the American Society for Aesthetic Plastic Surgery (ASAPS). In 2001, more than 1.6 million people received injections, an increase of 46 percent over the previous year. More popular than breast enhancement surgery, Botox is regarded by some as the ultimate fountain of youth.

Botulinum Toxin Type A (Botox Cosmetic) is a protein produced by the bacterium Clostridium botulinum
, which contains the same toxin that causes food poisoning. When used in a medical setting as an injectable form of sterile, purified botulinum toxin, small doses block the release of a chemical called acetylcholine by nerve cells that signal muscle contraction. By selectively interfering with the underlying muscles' ability to contract, existing frown lines are smoothed out and, in most cases, are nearly invisible in a week.

The procedure for injections is extremely easy and generally only takes a couple of minutes.  Also, no anesthesia is required for the injections.  The medication is injected with a fine needle into specific muscles with only minor discomfort.  It takes about 3 to 7 days for the drug to take full affect and it normally lasts about 4 months.  As the muscle returns to normal, the wrinkle will return.  The effects of this "miracle drug" are unfortunately temporary.   

There are several possible side effects, with only bruising as the most commonly seen.  Headaches, which resolve in 24-48 hours, can occur, but this is rare.  Eyelid drooping may also occur in a very small percentage of users, but it generally resolves in 3 weeks.  The development is usually caused by the migration of the Botox and for this reason you shouldn't rub the treated area for 12 hours after injections or lay down for 3-4 hours.  There have been no allergies associated with Botox to date, and if you are pregnant, breastfeeding, or have a neurological condition using this medication is not recommended. 

Remember, Botox is a drug, not a cosmetic.  Listed below are several questions you should ask your physician if you are looking into getting injections:

  • Ask about how it can help or hurt you.

  • Make sure your physician is trained in the use of Botox.
  • Make sure you get your treatment in a doctor's office or clinic.  Avoid Botox parties. 
  • Tell your physician in you have any nerve or muscle problems.
  • Tell your physician if you are taking antibiotics. 
  • Don't use Botox if you are pregnant or breast-feeding. 

To learn more about Botox contact the following:

  • American Academy of Dermatology  /  Phone: 1-888-462-3376
  • American Society for Dermatologic Surgery  /  Phone:  1800-441-27373
  • The official Botox web site:  www.botox.com

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